A sex-specific propensity-adjusted analysis of colonic adenoma detection rates in a screening cohort.

Sarah Wernly (Erstautor/-in), Bernhard Wernly (Co-Autor/-in), Georg Semmler, Sebastian Bachmayer, David Niederseer (Co-Autor/-in), Felix Stickel, Ursula Huber-Schönauer (Co-Autor/-in), Elmar Aigner (Co-Autor/-in), Christian Datz

Publikation: Beitrag in FachzeitschriftOriginalarbeitBegutachtung

18 Quellenangaben (Web of Science)

Abstract

The prevalence of colorectal adenoma and advanced adenoma (AA) differs between sexes. Also, the optimal age for the first screening colonoscopy is under debate. We, therefore, performed a sex-specific and age-adjusted comparison of adenoma, AA and advanced neoplasia (AN) rates in a real-world screening cohort. In total, 2824 asymptomatic participants between 45- and 60-years undergoing screening colonoscopy at a single-centre in Austria were evaluated. 46% were females and mean age was 53 ± 4 years. A propensity score for being female was calculated, and adenoma, AA and AN detection rates evaluated using uni- and multivariable logistic regression. Sensitivity analyses for three age groups (group 1: 45 to 49 years, n = 521, 41% females, mean age 47 ± 1 years; group 2: 50 to 54 years, n = 1164, 47% females, mean age 52 ± 1 years; group 3: 55 to 60 years, n = 1139, 46% females, mean age 57 ± 2 years) were performed. The prevalence of any adenoma was lower in females (17% vs. 30%; OR 0.46, 95% CI 0.38-0.55; p 
OriginalspracheEnglisch
Seiten (von - bis)17785
FachzeitschriftScientific reports
Jahrgang11
Ausgabenummer1
DOIs
PublikationsstatusVeröffentlicht - 7 Sept. 2021

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